Publications

Publications serve as the concrete art form for the scientist. It is his modus operandi. Authorship is akin to success and achievement. It cannot and should not deteriorate into a bargaining tool or commodity. Dardik
Kamatou, G., van Zyl, R.L., Van Vuuren, S.F., Viljoen, A.M., S.F., Figueiredo, A.C., Barroso, J.G., Pedro, L.G. 2006. Biological activities and composition of Salvia muirii L. Bol. essential oil Journal of Essential Oil Research 18: 48–51.

The essential oil of Salvia muirii L. Bol., a species indigenous to southern Africa was obtained by hydrodistillation (0.5%, v/f.w.) from the aerial parts and analyzed by GC and GC/MS. Thirty-nine components representing 98% of the
oil were identified. The oil was dominated by monoterpene hydrocarbons (53%) and oxygen-containing monoterpenes (36%) with 1,8-cineole (23%), a-pinene (22%) and limonene (12%) being the major components. The oil exhibited
potent antimalarial (IC50: 6 mg/mL) and antibacterial activity especially against Klebsiella pneumoniae and Bacillus cereus with MIC values of 6 and 9mg/mL, respectively. The oil exhibited poor anti-inflammatory and antioxidant activity. The 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide toxicity assay revealed that the essential oil of S. muirii should be used with caution as it displayed some degree of toxicity against the transformed human
kidney epithelial cells (IC50: 3 mg/mL).



Publications - TUT, Pretoria, Gauteng, South Africa [2010 © alvaroviljoen.com]