Publications

Publications serve as the concrete art form for the scientist. It is his modus operandi. Authorship is akin to success and achievement. It cannot and should not deteriorate into a bargaining tool or commodity. Dardik
Maree, J.E., Khondkar, P., Kwapong, A., Oyedemi, B.M., Aljarba, T.M., Stapleton, P., Viljoen, A.M., Gibbon, S. 2014. Bioactive acetophenones from Plectranthus venteri. Phytochemistry Letters 10: cxli-cxliv.

In a project to investigate the chemistry of South African Plectranthusspecies, from the dichloromethane extract of the aerial parts of Plectranthus venteri, we isolated two acetophenones, namely 2-hydroxy-3,4,5,6-tetramethoxy-acetophenone (1) and 2-hydroxy-4,5,6-trimethoxy-acetophenone (2). Structures were assigned using NMR spectroscopy and HRTOFESIMS. Compound 1 was previously synthesised as a precursor to the polymethoxylated flavone nobiletin. The acetophenones exhibited remarkable inhibitory activities against the transfer of the IncW plasmid R7K in a bacterial plasmid transfer inhibition assay.



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